The clinical application of cancer immunotherapy is unsatisfied due to low response rates and systemic immune-related adverse events.Microwave hyperthermia can be used as a synergistic immunotherapy to amplify the antitumor effect.Herein, we designed a Gd-based metal-organic framework (Gd-MOF) nanosystem for MRI-guided thermotherapy and synergistic

The text analyses the constitutive process of the Pedagogical Political Project (PPP) of a City Department of Education located Cat in the State of Rio Grande do Sul (Brazil), emphasizing the contributions of the collaborative action research while posture that feeds the political commitment, the critical thinking and cooperative relations for the

This study examines how factors influencing zero pledging vary with different levels of pledging in family-owned firms.This study uses a zero-inflated beta model to differentiate the lack of opposition to pledge from the positive endorsement of pledge in an institutional setting with regulatory pledging disclosure.Examining ownership behavior relat

Upogebia major (De Haan, 1841) is known for forming huge burrows in sandy, intertidal areas that can extend to depths of over 2 m.Despite its widespread distribution in East Asia and Russia, the genetic relatedness of its regional populations remains uncertain, likely owing to difficulties in specimen collection.Therefore, to appraise the phylogeog

Safety Carcinoid tumours of the appendix are uncommon incidentally detected tumours during histopathological examination following appendicectomy for acute appendicitis.Even though considered rare in children, they are the most frequently encountered tumours of the gastrointestinal tract.To our knowledge, carcinoid tumour of appendix in childhood h